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COL4A3BP / CERT is a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene.
Gene Name: | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
Family/Subfamily: | Collagen , not assigned-Collagen |
Synonyms: | COL4A3BP, Ceramide transfer protein, Ceramide transporter, CERT, CERTL, Lipid-transfer protein CERTL, HCERT, STARD11, GPBP |
Target Sequences: | NM_005713 NP_005704.1 Q9Y5P4 |
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