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COL17A1 / Collagen XVII

collagen, type XVII, alpha 1

COL17A1 / Collagen XVII is the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.

Gene Name: collagen, type XVII, alpha 1
Family/Subfamily: Collagen , not assigned-Collagen
Synonyms: COL17A1, Alpha 1 type XVII collagen, BA16H23.2, BP180, Bullous pemphigoid antigen 2, BPA-2, BPAG2, Collagen alpha-1(XVII) chain, Collagen, type XVII, alpha 1, Lad-1
Target Sequences: NM_000494 NP_000485.3 Q9UMD9

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Proteins (2)
Over-Expression Lysate (1)
Recombinant (1)
COL17A1 / Collagen XVII (2)
No (2)
His (1)
Myc-DDK (Flag) (1)
Human (1)
E. coli (1)
HEK 293 Cells (1)
COL17A1 / Collagen XVII Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
150.2 kDa
100 µg/$710
COL17A1 / Collagen XVII Protein - Recombinant Collagen Type XVII By SDS-PAGE
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E. coli
His
21.5 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).