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COASY

CoA synthase

Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms.

Gene Name: CoA synthase
Synonyms: COASY, NBP, Nucleotide binding protein, POV-2, CoA synthase, Coenzyme A synthase, DPCK, UKR1
Target Sequences: NM_025233 NP_079509.5 Q13057

☰ Filters
Antibodies (38)
Proteins (17)
Over-Expression Lysate (9)
Primary (38)
Recombinant (8)
COASY (55)
Human (38)
Mouse (13)
Rat (3)
Chimpanzee (3)
Gibbon (3)
Monkey (4)
Orangutan (3)
Pig (3)
IHC (5)
IHC-P (2)
WB (33)
Flo (6)
ELISA (14)
IF (3)
IP (2)
Peptide-ELISA (1)
rabbit (24)
mouse (14)
IgG (17)
IgG1 (2)
IgG1,k (7)
IgG2a (2)
IgG2b (2)
monoclonal mc (13)
polyclonal pc (25)
2A12 (1)
OTI2H1 (2)
OTI3B3 (2)
OTI3D5 (2)
APC Conjugated (2)
Biotin Conjugated (4)
Carrier-free (3)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (22)
aa319-368 (4)
Internal (1)
aa225-275 (1)
No (55)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
His-T7, N-terminus (1)
Myc-DDK (Flag) (13)
Human (12)
Mouse (1)
293T Cells (5)
E. coli (2)
HEK 293 Cells (8)
Wheat Germ Extract (2)
Purified (1)
COASY Antibody - IHC of paraffin-embedded Human breast tissue using anti-COASY mouse monoclonal antibody.
Select
COASY Mouse anti-Human Monoclonal (OTI3B3) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
COASY Antibody - IHC of paraffin-embedded Human breast tissue using anti-COASY mouse monoclonal antibody.
Select
COASY Mouse anti-Human Monoclonal (Carrier-free) (OTI3B3) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
COASY Antibody - IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-COASY mouse monoclonal antibody.
Select
COASY Mouse anti-Human Monoclonal (OTI2H1) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
COASY Antibody - IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-COASY mouse monoclonal antibody.
Select
COASY Mouse anti-Human Monoclonal (Carrier-free) (OTI2H1) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
COASY Antibody - Immunofluorescent analysis of Hela cells using COASY Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Select
COASY Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
COASY Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
COASY Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY COASY (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-COASY.
Select
COASY Mouse anti-Human Monoclonal (OTI3D5) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
COASY Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY COASY (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-COASY.
Select
COASY Mouse anti-Human Monoclonal (Carrier-free) (OTI3D5) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
Select
COASY Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
Select
COASY Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
Select
COASY Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
Select
COASY Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
Select
COASY Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
Select
COASY Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
COASY Antibody - Detection limit for recombinant GST tagged COASY is approximately 1 ng/ml as a capture antibody.
Select
COASY Mouse anti-Human Monoclonal (2A12) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Select
COASY Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
Select
COASY Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IP, WB
Unconjugated
100 µl/$749
COASY Antibody - Western blot analysis of COASY using COS7 whole cells lysates
Select
COASY Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
COASY Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Select
COASY Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
Select
COASY Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$749
Select
COASY Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
COASY Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
COASY Rabbit anti-Human Polyclonal (aa319-368) Antibody
Human
WB
Unconjugated
100 µl/$424
COASY Antibody - Western blot analysis of COASY expression in HeLa (A); A431 (B); Raw264.7 (C) whole cell lysates.
Select
COASY Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$299
COASY Antibody - Western blot analysis of extracts of various cell lines, using COASY antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 1s.
Select
COASY Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Viewing 1-25 of 55 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).