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COAA / RBM14
RNA binding motif protein 14
COAA / RBM14 is a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene.
| Gene Name: | RNA binding motif protein 14 |
| Synonyms: | RBM14, COAA, Paraspeckle protein 2, RNA-binding motif protein 14, RNA-binding protein 14, SIP, TMEM137, Transmembrane protein 137, PSP2, SYT-interacting protein, RNA binding motif protein 14, SYTIP1 |
| Target Sequences: | NM_006328 NP_006319.1 Q96PK6 |
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