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CNGA4

cyclic nucleotide gated channel alpha 4

Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.

Gene Name: cyclic nucleotide gated channel alpha 4
Family/Subfamily: Ion Channel , Cyclic nucleotide gated channel
Synonyms: CNGA4, CNG2B, Cgn2, CNG channel alpha-4, CNG-4, CNCA2, CNG4, CNG5, OCNC2, OCNCBETA, OCNCb, CNGB2
Target Sequences: AX465594 CAD42376.1 Q8IV77

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
CNGA4 (4)
No (4)
6His-SUMO, N-terminus (1)
GST (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (2)
CNGA4 Protein - 12.5% SDS-PAGE of human CNGA4 stained with Coomassie Blue
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Wheat Germ Extract
GST
92.4 kDa
10 µg/$479; 25 µg/$670
CNGA4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
65.8 kDa
20 µg/$215
CNGA4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
65.8 kDa
100 µg/$710
CNGA4 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His-SUMO, N-terminus
100 µg/$1,801; 20 µg/$1,247
Viewing 1-4 of 4 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).