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CNBP / ZNF9 is a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: | CCHC-type zinc finger, nucleic acid binding protein |
Synonyms: | CNBP, CNBP1, RNF163, Zinc finger protein 9, ZCCHC22, ZNF9, DM2, PROMM, Zinc finger protein 273 |
Target Sequences: | NM_003418 NP_003409.1 P62633 |
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