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CMA1 / Mast Cell Chymase

chymase 1, mast cell

CMA1 / MCT1 / Chymase is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants.

Gene Name: chymase 1, mast cell
Family/Subfamily: Protease , Serine S1
Synonyms: CMA1, Chymase, Chymase, heart, Chymase, mast cell, CYH, Mast cell chymase, Mcpt5, MCT1, Mast cell protease 5, Mast cell protease I, Heart chymase, Alpha-chymase, Chymase 1, Chymase 1, mast cell, CYM
Target Sequences: NM_001836 NP_001827.1 P23946

Publications (1)

1
The muscular expression of RAS in patients with achalasia. Casselbrant A, Kostic S, Lönroth H. Journal of the renin-angiotensin-aldosterone system : JRAAS. 2014 16:578-86. (WB; Human) [Full Text Article] [PubMed:24468662]

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CMA1 / Mast Cell Chymase (10)
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Tissue Homogenates (5)
CMA1 / Mast Cell Chymase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$783
CMA1 / Mast Cell Chymase ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
CMA1 / Mast Cell Chymase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
1 Plate/$579
CMA1 / Mast Cell Chymase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
CMA1 / Mast Cell Chymase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
12.5 - 800 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$748
CMA1 / Mast Cell Chymase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
CMA1 / Mast Cell Chymase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum, Tissue Homogenates
1 Plate/$968
CMA1 / Mast Cell Chymase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$586
CMA1 / Mast Cell Chymase ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$783
CMA1 / Mast Cell Chymase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78.125 - 5000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).