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Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates.
Gene Name: | caseinolytic mitochondrial matrix peptidase proteolytic subunit |
Family/Subfamily: | Protease , Serine S14 |
Synonyms: | CLPP, Endopeptidase Clp |
Target Sequences: | NM_006012 NP_006003.1 Q16740 |
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