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CLK3

CDC-like kinase 3

Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.

Gene Name: CDC-like kinase 3
Family/Subfamily: Protein Kinase , LAMMER/Clk
Synonyms: CLK3, PHCLK3/152, CDC-like kinase 3, Hclk3, PHCLK3
Target Sequences: NM_003992 NP_003983.2 P49761

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
CLK3 (4)
No (4)
GST (2)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
Baculovirus (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (1)
CLK3 Protein - 12.5% SDS-PAGE of human CLK3 stained with Coomassie Blue
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Wheat Germ Extract
GST
85 kDa
10 µg/$479; 25 µg/$670
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Baculovirus
GST
Less than 1.0 EU/µg protein (determined by LAL method).
85 kDa
50 µg/$502
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HEK 293 Cells
Myc-DDK (Flag)
58.4 kDa
100 µg/$494
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293T Cells
Myc-DDK (Flag)
58.4 kDa
20 µg/$150
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).