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Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.
Gene Name: | C-type lectin domain family 9, member A |
Synonyms: | CLEC9A, DNGR1, HEEE9341, NAC, UNQ9341, DNGR-1, CD370 |
Target Sequences: | Q6UXN8 Q6UXN8 |
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