CLEC6A / Dectin 2

C-type lectin domain family 6, member A

Binds high-mannose carbohydrates in a Ca2+-dependent manner. Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

CLEC6A / Dectin 2 (4)

Publications

No (4)

Tag

His (1)

Human IgG1 Fc (1)

Myc-DDK (Flag) (2)

Species

Human (1)

Mouse (2)

Source

293T Cells (1)

HEK 293 Cells (2)

Human Cells (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

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Human CLEC6A / Dectin 2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93163

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.8 kDa

Price:

20 µg/$150

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CLEC6A / Dectin 2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122069

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.8 kDa

Price:

100 µg/$494

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Mouse CLEC6A / Dectin 2 Protein (Recombinant Human IgG1 Fc) (aa45-209) - LS-G3969

Source:

HEK 293 Cells

Tag:

Human IgG1 Fc

Endotoxin Level:

Less than 0.01 EU/µg protein (determined by LAL method).

Molecular Weight:

~58kDa (SDS-PAGE)

Price:

50 µg/$414

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Mouse CLEC6A / Dectin 2 Protein (Recombinant His) (Ile44-Leu209) - LS-G98108

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

20.9 kDa

Price:

100 µg/$721

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