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CLEC1A / CLEC-1 encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The encoded protein may play a role in regulating dendritic cell function. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. Alternative splicing results in multiple transcript variants.
Gene Name: | C-type Lectin Domain Family 1, Member A |
Synonyms: | CLEC1A, C-type lectin-like receptor 1, C-type lectin-like receptor-1, CLEC-1, CLEC1 |
Target Sequences: | NM_016511 NP_057595.2 Q8NC01 |
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