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CLEC12A / CD371
C-type Lectin Domain Family 12, Member A
CLEC12A is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.
| Gene Name: | C-type Lectin Domain Family 12, Member A |
| Synonyms: | CLEC12A, C-type lectin-like molecule 1, C-type lectin protein CLL-1, DCAL-2, DCAL2, CLL1, MICL, C-type lectin superfamily, C-type lectin-like molecule-1, CLL-1, CD371 |
| Target Sequences: | NM_138337 NP_612210.4 Q5QGZ9 |
Publications (1)
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