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CLEC12A / CD371

C-type Lectin Domain Family 12, Member A

CLEC12A is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.

Gene Name: C-type Lectin Domain Family 12, Member A
Synonyms: CLEC12A, C-type lectin-like molecule 1, C-type lectin protein CLL-1, DCAL-2, DCAL2, CLL1, MICL, C-type lectin superfamily, C-type lectin-like molecule-1, CLL-1, CD371
Target Sequences: NM_138337 NP_612210.4 Q5QGZ9

Publications (1)

1
Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease. Sebastian Werneburg, Jonathan Jung, Rejani B Kunjamma, Seung-Kwon Ha, Nicholas J Luciano, Cory M Willis, Guangping Gao, Natalia P Biscola, Leif A Havton, Stephen J Crocker, Brian Popko, Daniel S Reich, Dorothy P Schafer. Immunity. 2020 January;52:167-182.e7. [Full Text Article] [PubMed:31883839] [PMC:PMC6996144] Related Antibodies: LS-C377776.

☰ Filters
Antibodies (17)
Proteins (10)
ELISA Kits (2)
Custom (1)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (4)
Primary (17)
Recombinant (5)
Sandwich (1)
CLEC12A / CD371 (29)
Human (18)
Mouse (3)
Rat (1)
IHC (4)
IHC-P (3)
WB (15)
Flo (2)
ELISA (11)
ICC (1)
Peptide-ELISA (1)
SDS-PAGE (1)
rabbit (14)
mouse (2)
goat (1)
IgG (10)
IgG1 (1)
IgG2a (1)
monoclonal mc (2)
polyclonal pc (15)
4D5A8 (1)
6B3G8 (1)
96-Well Strip Plate (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (12)
aa178-206 (7)
aa66-265 (2)
C Terminus (1)
aa170-220 (1)
No (28)
Yes (1)
Plasma (1)
Serum (1)
10His, N-terminus + Myc, C-terminus (1)
6His, N-terminus (1)
GST, N-terminus (1)
His (1)
His, N-Terminal (1)
His,N-terminus (1)
Myc-DDK (Flag) (4)
Human (7)
Mouse (1)
293T Cells (2)
Baculovirus (1)
HEK 293 Cells (6)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (2)
CLEC12A / CD371 Antibody - Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
Select
CLEC12A / CD371 Rabbit anti-Human Polyclonal (aa66-265) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
CLEC12A / CD371 Antibody - Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
Select
CLEC12A / CD371 Rabbit anti-Human Polyclonal (aa66-265) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CLEC12A / CD371 Antibody - Western blot analysis of extracts of various cell lines, using CLEC12A antibody.
Select
CLEC12A / CD371 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CLEC12A / CD371 Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Select
HEK 293 Cells
His, N-Terminal
~37-50 kDa
10 µg/$289; 50 µg/$360
CLEC12A / CD371 Antibody - Immunochemical staining of human CLEC12A in human spleen with rabbit polyclonal antibody at 1:5000 dilution, formalin-fixed paraffin embedded sections.
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CLEC12A / CD371 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
CLEC12A / CD371 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Select
HEK 293 Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
26 kDa
100 µg/$1,189; 1 mg/$5,985
CLEC12A / CD371 Antibody - Western blot analysis using CLL1 mAb against HEK293 (1) and CLL1 (AA: extra 65-265)-hIgGFc transfected HEK293 (2) cell lysate.
Select
CLEC12A / CD371 Mouse anti-Human Monoclonal (6B3G8) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
Select
CLEC12A / CD371 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
CLEC12A / CD371 Antibody - Immunofluorescence analysis of Hela cells using CLL1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Select
CLEC12A / CD371 Mouse anti-Human Monoclonal (4D5A8) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
100 µg/$459
CLEC12A / CD371 Antibody - Antibody (0.3µg/ml) staining of U937 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Select
CLEC12A / CD371 Goat anti-Human Polyclonal (C Terminus) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
CLEC12A / CD371 Antibody - CLEC12A Antibody western blot of ZR-75-1 cell line lysates (35 ug/lane). The CLEC12A antibody detected the CLEC12A protein (arrow).
Select
CLEC12A / CD371 Rabbit anti-Human Polyclonal (aa178-206) Antibody
Human
WB
Unconjugated
400 µl/$393
Select
CLEC12A / CD371 Rabbit anti-Human Polyclonal (aa178-206) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
CLEC12A / CD371 Rabbit anti-Human Polyclonal (aa178-206) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
CLEC12A / CD371 Rabbit anti-Human Polyclonal (aa178-206) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
CLEC12A / CD371 Rabbit anti-Human Polyclonal (aa178-206) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
CLEC12A / CD371 Rabbit anti-Human Polyclonal (aa178-206) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
CLEC12A / CD371 Rabbit anti-Human Polyclonal (aa178-206) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
CLEC12A / CD371 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
CLEC12A / CD371 Antibody - Western Blot: CLEC12A Antibody - Analysis of CLEC12A using CLEC12A antibody. ThP1 cell lysate in the 1) absence and 2) presence of immunizing peptide probed with 2 ug/ml of CLEC12A antibody. I goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Select
CLEC12A / CD371 Rabbit anti-Human Polyclonal (aa170-220) Antibody
Human
WB
Unconjugated
0.1 mg/$386
CLEC12A / CD371 Protein
Select
HEK 293 Cells
His,N-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human CLEC12A consists of 221 amino acids and has a calculated molecular mass of 26 kDa. The apparent molecular mass of rhCLEC12A is approximately 40-45 kDa in SDS-PAGE under reducing conditions.
100 µg/$519; 1 mg/$2,551
CLEC12A / CD371 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CLEC12A / CD371 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
30.6 kDa
20 µg/$150
CLEC12A / CD371 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
27.1 kDa
20 µg/$150
CLEC12A / CD371 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
1 Plate/$669
Viewing 1-25 of 29 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).