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CLDN8 / Claudin 8
claudin 8
CLDN8 / Claudin 8 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.
| Gene Name: | claudin 8 |
| Family/Subfamily: | Claudin , not assigned-Claudin |
| Synonyms: | CLDN8, Claudin 8, Claudin-8 |
| Target Sequences: | NM_199328 AAH58004.1 P56748 |
Publications (1)
1
Glucocorticoids Regulate Tight Junction Permeability of Lung Epithelia by Modulating Claudin 8. Kielgast F, Schmidt H, Braubach P, Winkelmann VE, Thompson KE, Frick M, Dietl P, Wittekindt OH. American journal of respiratory cell and molecular biology. 2016 54:707-17. (ICC; Human)
[Full Text Article]
[PubMed:26473470]
Related Antibodies: LS-B5505.
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Antibodies
(28)
Type
Primary
(28)
Target
CLDN8 / Claudin 8
(28)
Reactivity
Human
(21)
Mouse
(8)
Rat
(7)
Bovine
(3)
Chimpanzee
(3)
Dog
(6)
Monkey
(1)
Application
IHC
(14)
IHC-Fr
(1)
IHC-P
(7)
WB
(25)
Flo
(7)
ELISA
(10)
IF
(6)
Peptide-ELISA
(2)
Host
rabbit
(27)
mouse
(1)
Product Group
IHCPlus
(3)
Isotype
IgG
(25)
Clonality
polyclonal pc
(28)
Format
APC Conjugated
(2)
Azide-free
(1)
Biotin Conjugated
(3)
FITC Conjugated
(3)
HRP Conjugated
(3)
PE Conjugated
(2)
Unconjugated
(15)
Epitope
aa140-166
(7)
C-Terminus
(5)
50-130 aa, Internal
(1)
Internal
(1)
aa141-225
(1)
aa81-130
(1)
Publications
No
(27)
Yes
(1)
CLDN8 / Claudin 8 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Mouse, Dog, Rat
IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$485
CLDN8 / Claudin 8 Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse, Dog, Rat
IHC, WB
HRP Conjugated
100 µl/$1,017
CLDN8 / Claudin 8 Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse, Dog, Rat
IF, IHC, WB
Biotin Conjugated
100 µl/$1,017
CLDN8 / Claudin 8 Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse, Dog, Rat
IF, IHC, WB
FITC Conjugated
100 µl/$1,017
CLDN8 / Claudin 8 Rabbit anti-Mouse Polyclonal (PE) Antibody
Mouse, Dog, Rat
IF, IHC, WB
PE Conjugated
100 µl/$1,017
CLDN8 / Claudin 8 Rabbit anti-Mouse Polyclonal (APC) Antibody
Mouse, Dog, Rat
IF, IHC, WB
APC Conjugated
100 µl/$1,017
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal (aa140-166) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$460
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Bovine, Human, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Bovine, Human, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Bovine, Human, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal (aa141-225) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal (aa140-166) Antibody
Human
Flo, WB
Unconjugated
200 µl/$734
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal (aa140-166) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal (aa140-166) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal (aa140-166) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal (aa140-166) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal (aa140-166) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal (50-130 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal (aa81-130) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CLDN8 / Claudin 8 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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product results
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