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CLDN6 / Claudin 6

claudin 6

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

Gene Name: claudin 6
Family/Subfamily: Claudin , not assigned-Claudin
Synonyms: CLDN6, Claudin-6, Claudin 6, Skullin
Target Sequences: NM_021195 NP_067018.2 P56747

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Products
Antibodies (47)
Primary (47)
CLDN6 / Claudin 6 (47)
Human (44)
Mouse (19)
Rat (3)
Bovine (3)
Gibbon (3)
Monkey (4)
Pig (3)
Rabbit (3)
IHC (11)
IHC-P (6)
WB (39)
ELISA (12)
ICC (1)
IF (18)
Peptide-ELISA (5)
rabbit (32)
mouse (15)
Product Group
IHCPlus (1)
IgG (22)
IgG1 (15)
monoclonal mc (15)
polyclonal pc (32)
OTI2A3 (2)
OTI2H1 (2)
OTI3E3 (2)
OTI3G3 (2)
OTI4B5 (2)
OTI4B6 (2)
OTI5D2 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
Carrier-free (7)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (33)
aa130-159 (7)
C-Terminus (4)
pTyr219 (3)
50-130 aa, Internal (1)
Val118 (1)
aa103-137 (1)
aa146-180 (1)
aa186-229 (1)
aa81-130 (1)
No (47)
CLDN6 / Claudin 6 Antibody - Anti-CLDN6 / Claudin 6 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CLDN6 / Claudin 6 Rabbit anti-Human Polyclonal (Val118) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CLDN6 / Claudin 6 Antibody - Immunohistochemical analysis of Claudin 6 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX. w
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CLDN6 / Claudin 6 Rabbit anti-Human Polyclonal (aa103-137) Antibody
Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
CLDN6 / Claudin 6 Antibody - Immunohistochemistry analysis of paraffin-embedded human ovary tissue, using CLDN6 Antibody. The picture on the right is blocked with the synthesized peptide.
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CLDN6 / Claudin 6 Rabbit anti-Human Polyclonal (aa81-130) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CLDN6 / Claudin 6 Antibody - Anti-CLDN6 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CLDN6.
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CLDN6 / Claudin 6 Mouse anti-Human Monoclonal (OTI3E3) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
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CLDN6 / Claudin 6 Rabbit anti-Human Polyclonal (aa130-159) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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CLDN6 / Claudin 6 Rabbit anti-Human Polyclonal (aa130-159) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
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CLDN6 / Claudin 6 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$361; 100 µl/$421
CLDN6 / Claudin 6 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CLDN6 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CLDN6.
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CLDN6 / Claudin 6 Mouse anti-Human Monoclonal (OTI2A3) Antibody
Human
WB
Unconjugated
100 µl/$434
CLDN6 / Claudin 6 Antibody - CLDN6 Antibody western blot of mouse heart tissue lysates (35 ug/lane). The CLDN6 antibody detected the CLDN6 protein (arrow).
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CLDN6 / Claudin 6 Rabbit anti-Human Polyclonal (aa130-159) Antibody
Mouse, Human
WB
Unconjugated
200 µl/$393
CLDN6 / Claudin 6 Antibody - Anti-CLDN6 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CLDN6.
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CLDN6 / Claudin 6 Mouse anti-Human Monoclonal (OTI4B6) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
CLDN6 / Claudin 6 Antibody - Anti-CLDN6 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CLDN6.
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CLDN6 / Claudin 6 Mouse anti-Human Monoclonal (OTI3G3) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
CLDN6 / Claudin 6 Antibody - Anti-CLDN6 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CLDN6.
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CLDN6 / Claudin 6 Mouse anti-Human Monoclonal (OTI4B5) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
CLDN6 / Claudin 6 Antibody - Anti-CLDN6 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CLDN6.
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CLDN6 / Claudin 6 Mouse anti-Human Monoclonal (Carrier-free) (OTI4B5) Antibody
Human
IF, WB
Unconjugated, Carrier-free
100 µg/$511
CLDN6 / Claudin 6 Antibody - CLDN6 / Claudin 6 antibody Western blot of Mouse Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CLDN6 / Claudin 6 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
WB
Unconjugated
100 µl/$424
CLDN6 / Claudin 6 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CLDN6 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CLDN6.
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CLDN6 / Claudin 6 Mouse anti-Human Monoclonal (OTI5D2) Antibody
Human
WB
Unconjugated
100 µl/$434
CLDN6 / Claudin 6 Antibody - 1:100 staining human liver tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CLDN6 / Claudin 6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CLDN6 / Claudin 6 Antibody - Western blot of Claudin-6 antibody
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CLDN6 / Claudin 6 Rabbit anti-Human Polyclonal (50-130 aa, Internal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CLDN6 / Claudin 6 Antibody - Western blot of CLDN6 expression in Jurkat cells
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CLDN6 / Claudin 6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
CLDN6 / Claudin 6 Antibody - Anti-CLDN6 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CLDN6.
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CLDN6 / Claudin 6 Mouse anti-Human Monoclonal (OTI2H1) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
CLDN6 / Claudin 6 Antibody - Western blot of lysate from mouse kidney tissue lysate, using Cldn6 antibody diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20 ug.
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CLDN6 / Claudin 6 Rabbit anti-Mouse Polyclonal (aa186-229) Antibody
Mouse
Peptide-ELISA, WB
Unconjugated
400 µl/$393
CLDN6 / Claudin 6 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human ovary tissue using CLDN6 antibody.
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CLDN6 / Claudin 6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
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CLDN6 / Claudin 6 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
100 µl/$386
CLDN6 / Claudin 6 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CLDN6 / Claudin 6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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CLDN6 / Claudin 6 Rabbit anti-Human Polyclonal (pTyr219) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CLDN6 / Claudin 6 Antibody - Immunohistochemistry image of paraffin-embedded human liver tissue at a dilution of 1:100
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CLDN6 / Claudin 6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Viewing 1-25 of 47 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).