CLDN18 / Claudin 18

claudin 18

CLDN18 / Claudin 18 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Products

Proteins (4)

Type

Recombinant (4)

Target

CLDN18 / Claudin 18 (4)

Publications

No (4)

Tag

GST (1)

GST, N-terminus (1)

His,N-terminus (2)

Species

Human (4)

Source

E. coli (2)

Wheat Germ Extract (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

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Human CLDN18 / Claudin 18 Protein (Recombinant GST) (Full Length) - LS-G33677

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

54.3 kDa

Price:

2 µg/$439

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Human CLDN18 / Claudin 18 Protein (Recombinant GST, N-terminus) (aa196-261) - LS-G62426

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CLDN18 / Claudin 18 Protein (Recombinant His,N-terminus) (Asp28-Leu76) - LS-G140791

Source:

E. coli

Tag:

His,N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

19.7 kDa

Price:

10 µg/$479; 50 µg/$805

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Human CLDN18 / Claudin 18 Protein (Recombinant His,N-terminus) (Asp28-Leu76) - LS-G140792

Source:

E. coli

Tag:

His,N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

19.8 kDa

Price:

10 µg/$479; 50 µg/$805

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