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Vector Laboratories, Inc.
6737 Mowry Ave
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CLDN18 / Claudin 18
claudin 18
CLDN18 / Claudin 18 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
| Gene Name: | claudin 18 |
| Family/Subfamily: | Claudin , not assigned-Claudin |
| Synonyms: | CLDN18, Claudin 18, Claudin-18, SFTPJ, SFTA5, Surfactant associated 5 |
| Target Sequences: | NM_016369 NP_057453.1 P56856 |
Publications (1)
1
Mast cells play an important role in chlamydia pneumoniae lung infection by facilitating immune cell recruitment into the airway. Norika Chiba, Kenichi Shimada, Shuang Chen, Heather D Jones, Randa Alsabeh, Anatoly V Slepenkin, Ellena Peterson, Timothy R Crother, Moshe Arditi. Journal of immunology (Baltimore, Md. : 1950). 2015 April;194:3840-51. [Full Text Article]
[PubMed:25754739]
[PMC:PMC4390505]
Related Antibodies: LS-C816125.
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CLDN18 / Claudin 18
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CLDN18 / Claudin 18 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$460
CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Mouse, Dog, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Mouse, Dog, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Mouse, Dog, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (aa143-192) Antibody
Human
WB
Unconjugated
100 µl/$424
CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (aa143-192) (HRP) Antibody
Chicken, Bovine, Rabbit, Mouse, Rat, Pig, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (aa143-192) (Biotin) Antibody
Chicken, Bovine, Rabbit, Mouse, Rat, Pig, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (aa143-192) (FITC) Antibody
Chicken, Bovine, Rabbit, Mouse, Rat, Pig, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
Sandwich
96-Well Microplate
Human
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
CLDN18 / Claudin 18 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IP
Unconjugated
100 µg/$351
CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
50 µl/$317; 100 µl/$375; 200 µl/$473
CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Wheat Germ Extract
GST
54.3 kDa
2 µg/$439
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
CLDN18 / Claudin 18 Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
IF, IHC, WB
HRP Conjugated
100 µl/$1,017
CLDN18 / Claudin 18 Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
IF, IHC, WB
Biotin Conjugated
100 µl/$1,017
CLDN18 / Claudin 18 Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse
IF, IHC, WB
FITC Conjugated
100 µl/$1,017
CLDN18 / Claudin 18 Rabbit anti-Mouse Polyclonal (APC) Antibody
Mouse
IF, IHC, WB
APC Conjugated
100 µl/$1,017
CLDN18 / Claudin 18 Rabbit anti-Mouse Polyclonal (PE) Antibody
Mouse
IF, IHC, WB
PE Conjugated
100 µl/$1,017
CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
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