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CLDN11 / Claudin 11

claudin 11

CLDN11 / Claudin 11 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: claudin 11
Family/Subfamily: Claudin , not assigned-Claudin
Synonyms: CLDN11, Claudin-11, OSP, OTM, Claudin 11
Target Sequences: NM_005602 NP_005593.2 O75508

Publications (1)

1
Restoration of desmosomal junction protein expression and inhibition of H3K9-specific histone demethylase activity by cytostatic proline-rich polypeptide-1 leads to suppression of tumorigenic potential in human chondrosarcoma cells. Galoian K, Qureshi A, Wideroff G, Temple HT. Molecular and clinical oncology. 2015 3:171-178. (WB; Human) [Full Text Article] [PubMed:25469290] [PMC:PMC4251108] Related Antibodies: LS-C6168.

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ELISA Kits (10)
Cell-Based (1)
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CLDN11 / Claudin 11 (10)
Human (5)
Mouse (1)
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Chicken (1)
Guinea pig (1)
Monkey (1)
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96-Well Microplate (2)
96-Well Strip Plate (7)
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Adherent Cell Cultures (1)
Plasma (4)
Serum (4)
Tissue Homogenates (2)
CLDN11 / Claudin 11 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
CLDN11 / Claudin 11 ELISA Kit
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Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
CLDN11 / Claudin 11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$730
CLDN11 / Claudin 11 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
CLDN11 / Claudin 11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CLDN11 / Claudin 11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CLDN11 / Claudin 11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CLDN11 / Claudin 11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CLDN11 / Claudin 11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CLDN11 / Claudin 11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).