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CLDN11 / Claudin 11
claudin 11
CLDN11 / Claudin 11 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.
| Gene Name: | claudin 11 |
| Family/Subfamily: | Claudin , not assigned-Claudin |
| Synonyms: | CLDN11, Claudin-11, OSP, OTM, Claudin 11 |
| Target Sequences: | NM_005602 NP_005593.2 O75508 |
Publications (1)
1
Restoration of desmosomal junction protein expression and inhibition of H3K9-specific histone demethylase activity by cytostatic proline-rich polypeptide-1 leads to suppression of tumorigenic potential in human chondrosarcoma cells. Galoian K, Qureshi A, Wideroff G, Temple HT. Molecular and clinical oncology. 2015 3:171-178. (WB; Human)
[Full Text Article]
[PubMed:25469290]
[PMC:PMC4251108]
Related Antibodies: LS-C6168.
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CLDN11 / Claudin 11
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Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
ELISA, IF, IP, WB
Unconjugated
100 µg/$740
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Human
ELISA, IF, IP, WB
HRP Conjugated
100 µl/$982
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
ELISA, IF, IP, WB
Biotin Conjugated
100 µl/$982
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
ELISA, IF, IP, WB
FITC Conjugated
100 µl/$982
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (APC) Antibody
Mouse, Human
ELISA, IF, IP, WB
APC Conjugated
100 µl/$982
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Human
ELISA, IF, IP, WB
PE Conjugated
100 µl/$982
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (aa158-207) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µg/$331
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (Ser198) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
250 µl/$505
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (130-210 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$386
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