CISH / SOCS

cytokine inducible SH2-containing protein

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

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Products

Antibodies (39)

Proteins (10)

Type

Over-Expression Lysate (4)

Primary (39)

Recombinant (6)

Target

CISH / SOCS (49)

Reactivity

Human (29)

Mouse (22)

Rat (12)

Bat (3)

Bovine (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Horse (3)

Monkey (3)

Pig (4)

Rabbit (3)

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Application

IHC (4)

IHC-P (3)

WB (35)

ELISA (3)

ICC (1)

IF (2)

Peptide-ELISA (1)

Host

rabbit (38)

mouse (1)

Product Group

IHCPlus (1)

Isotype

IgG (12)

Clonality

polyclonal pc (39)

Format

APC (2)

APC Conjugated (3)

Biotin Conjugated (4)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (3)

Unconjugated (17)

Epitope

aa1-258 (9)

aa79-256 (8)

aa78-127 (4)

Internal (1)

aa1-257 (1)

aa241-258 (1)

Publications

No (49)

Tag

GST (2)

GST, N-terminus (1)

GST, N-terminus + His, C-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (4)

Species

Human (7)

Mouse (1)

Source

293T Cells (2)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

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Human CISH / SOCS Protein (Recombinant GST, N-terminus) (aa1-258) - LS-G56981

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human CISH / SOCS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82339

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.5 kDa

Price:

20 µg/$150

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CISH / SOCS Antibody (aa241-258) LS-C312931

Antibody:

CISH / SOCS Rabbit anti-Human Polyclonal (aa241-258) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$470

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CISH / SOCS Antibody (aa1-258) LS-C374453

Antibody:

CISH / SOCS Rabbit anti-Human Polyclonal (aa1-258) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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Human CISH / SOCS Protein (Recombinant His-T7) (aa1-258) - LS-G24821

Source:

E. coli

Tag:

His-T7

Molecular Weight:

32.4 kDa

Price:

10 µg/$249; 50 µg/$307; 100 µg/$385; 200 µg/$482; 1 mg/$1,325; 500 µg/$962; 5 mg/$2,204; 2 mg/$1,480

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CISH / SOCS Antibody (aa78-127) LS-C135290

Antibody:

CISH / SOCS Rabbit anti-Mouse Polyclonal (aa78-127) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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CISH / SOCS Antibody (aa78-127, HRP) LS-C456611

Antibody:

CISH / SOCS Rabbit anti-Mouse Polyclonal (aa78-127) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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CISH / SOCS Antibody (aa78-127, Biotin) LS-C456609

Antibody:

CISH / SOCS Rabbit anti-Mouse Polyclonal (aa78-127) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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CISH / SOCS Antibody (aa78-127, FITC) LS-C456610

Antibody:

CISH / SOCS Rabbit anti-Mouse Polyclonal (aa78-127) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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IHC-plus™ CISH / SOCS Antibody (aa1-257) LS-B15192

(4.0) Rating

Antibody:

CISH / SOCS Rabbit anti-Human Polyclonal (aa1-257) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$375

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CISH / SOCS Antibody LS-C412161

Antibody:

CISH / SOCS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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CISH / SOCS Antibody LS-C813820

Antibody:

CISH / SOCS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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CISH / SOCS Antibody LS-C335649

Antibody:

CISH / SOCS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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CISH / SOCS Antibody (aa1-258) LS-C128171

Antibody:

CISH / SOCS Mouse anti-Human Polyclonal (aa1-258) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$705

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CISH / SOCS Antibody LS-C780619

Antibody:

CISH / SOCS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC-P

Format:

Unconjugated

Price:

100 µl/$357

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CISH / SOCS Antibody LS-C807456

Antibody:

CISH / SOCS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$282; 200 µl/$350

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CISH / SOCS Antibody LS-C833321

Antibody:

CISH / SOCS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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CISH / SOCS Antibody (aa79-256) LS-C374452

Antibody:

CISH / SOCS Rabbit anti-Mouse Polyclonal (aa79-256) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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CISH / SOCS Antibody (aa79-256, FITC) LS-C693832

Antibody:

CISH / SOCS Rabbit anti-Mouse Polyclonal (aa79-256) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

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CISH / SOCS Antibody (aa79-256, Cy3) LS-C702392

Antibody:

CISH / SOCS Rabbit anti-Mouse Polyclonal (aa79-256) (Cy3) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

• Unconjugated
• FITC
• Cy3

• Unconjugated
• FITC
• Cy3

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CISH / SOCS Antibody LS-C309917

Antibody:

CISH / SOCS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

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CISH / SOCS Antibody LS-C340924

Antibody:

CISH / SOCS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

CISH / SOCS Antibody LS-C749528

Antibody:

CISH / SOCS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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CISH / SOCS Antibody LS-C356793

Antibody:

CISH / SOCS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$386

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CISH / SOCS Antibody (Internal) LS-C352004

Antibody:

CISH / SOCS Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Pig, Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$255; 50 µl/$271; 100 µl/$299; 200 µl/$351

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