CIITA

class II, major histocompatibility complex, transactivator

Essential for transcriptional activity of the HLA class II promoter; activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. May act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter. Also mediates enhanced MHC class I transcription; the promoter element requirements for CIITA-mediated transcription are distinct from those of constitutive MHC class I transcription, and CIITA can functionally replace TAF1 at these genes. Exhibits intrinsic GTP-stimulated acetyltransferase activity. Exhibits serine/threonine protein kinase activity: can phosphorylate the TFIID component TAF7, the RAP74 subunit of the general transcription factor TFIIF, histone H2B at 'Ser-37' and other histones (in vitro).

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Products

Antibodies (21)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (21)

Recombinant (1)

Target

CIITA (24)

Reactivity

Human (17)

Mouse (13)

Rat (9)

Bovine (3)

Chimpanzee (3)

Dog (6)

Gibbon (3)

Guinea pig (3)

Monkey (3)

Application

IHC (2)

IHC-P (3)

WB (21)

ELISA (7)

IF (2)

IP (2)

Peptide-ELISA (2)

Host

rabbit (18)

mouse (3)

Product Group

IHCPlus (1)

Isotype

IgG (11)

IgG1 (3)

Clonality

monoclonal mc (3)

polyclonal pc (18)

Clone

OTI7B12 (2)

Format

Biotin Conjugated (2)

Carrier-free (1)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (15)

Epitope

C-Terminus (4)

aa841-890 (4)

aa414-724 (2)

680-760 aa, Internal (1)

N-Terminus (1)

aa706-755 (1)

Publications

No (24)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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IHC-plus™ CIITA Antibody LS-B5490

(4.0) Rating

Antibody:

CIITA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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CIITA Antibody LS-C89041

Antibody:

CIITA Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$842

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CIITA Antibody (aa414-724, clone OTI7B12) LS-C796288

Antibody:

CIITA Mouse anti-Human Monoclonal (aa414-724) (OTI7B12) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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CIITA Antibody (aa414-724, clone OTI7B12, Carrier-free) LS-C792979

Antibody:

CIITA Mouse anti-Human Monoclonal (aa414-724) (Carrier-free) (OTI7B12) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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CIITA Antibody (aa706-755) LS-C118863

Antibody:

CIITA Rabbit anti-Human Polyclonal (aa706-755) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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CIITA Antibody LS-C19057

Antibody:

CIITA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$567

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CIITA Antibody (aa841-890) LS-C30116

Antibody:

CIITA Rabbit anti-Mouse Polyclonal (aa841-890) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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CIITA Antibody (aa841-890, HRP) LS-C434795

Antibody:

CIITA Rabbit anti-Mouse Polyclonal (aa841-890) (HRP) Antibody

Reactivity:

Mouse, Dog

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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CIITA Antibody (aa841-890, Biotin) LS-C434794

Antibody:

CIITA Rabbit anti-Mouse Polyclonal (aa841-890) (Biotin) Antibody

Reactivity:

Mouse, Dog

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

CIITA Antibody (aa841-890, FITC) LS-C434796

Antibody:

CIITA Rabbit anti-Mouse Polyclonal (aa841-890) (FITC) Antibody

Reactivity:

Mouse, Dog

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

CIITA Antibody LS-C662465

Antibody:

CIITA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

CIITA Antibody LS-C810185

Antibody:

CIITA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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CIITA Antibody LS-C6094

Antibody:

CIITA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µl/$917

Select

CIITA Antibody LS-C781815

Antibody:

CIITA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

Select

CIITA Antibody (N-Terminus) LS-C19058

Antibody:

CIITA Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$567

Select

CIITA Antibody (680-760 aa, Internal) LS-C382720

Antibody:

CIITA Rabbit anti-Human Polyclonal (680-760 aa, Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

CIITA Antibody LS-C822698

Antibody:

CIITA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

CIITA Antibody (C-Terminus) LS-C110229

Antibody:

CIITA Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

CIITA Antibody (C-Terminus, HRP) LS-C436262

Antibody:

CIITA Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

CIITA Antibody (C-Terminus, Biotin) LS-C436259

Antibody:

CIITA Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

CIITA Antibody (C-Terminus, FITC) LS-C436261

Antibody:

CIITA Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

Human CIITA Protein (Recombinant GST, N-terminus) (aa39-148) - LS-G59239

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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CIITA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123314

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

123.2 kDa

Price:

100 µg/$710

Select

Human CIITA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87475

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

123.2 kDa

Price:

20 µg/$215

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