Chymotrypsin

Chymotrypsin is a digestive enzyme component of pancreatic juice acting in the duodenum where it performs proteolysis, the breakdown of proteins and polypeptides. Chymotrypsin preferentially cleaves peptide amide bonds where the carboxyl side of the amide bond (the P1 position) is a large hydrophobic amino acid (tyrosine, tryptophan, and phenylalanine). These amino acids contain an aromatic ring in their sidechain that fits into a 'hydrophobic pocket' (the S1 position) of the enzyme. It is activated in the presence of trypsin. The hydrophobic and shape complementarity between the peptide substrate P1 sidechain and the enzyme S1 binding cavity accounts for the substrate specificity of this enzyme. Chymotrypsin also hydrolyzes other amide bonds in peptides at slower rates, particularly those containing leucine and methionine at the P1 position. In human there are three isoenzymes, chymotrypsinogen B1, chymotrypsinogen B2, and chymotrypsinogen C.

Chymotrypsin Target Details

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Products

Antibodies (14)

Type

Primary (14)

Target

Chymotrypsin (14)

Reactivity

Human (6)

Mouse (1)

Rat (1)

Bovine (8)

Cow (8)

Application

IHC (5)

IHC-Fr (1)

IHC-P (5)

WB (13)

ELISA (2)

ICC (8)

IP (8)

Host

rabbit (9)

mouse (5)

Product Group

IHCPlus (1)

Isotype

IgG1 (3)

IgG3 (2)

Clonality

monoclonal mc (5)

polyclonal pc (9)

Clone

CHYMO10-101.2 (1)

CHYMO10-104.10 (1)

CHYMO10-104.5 (1)

Format

APC (1)

APC Conjugated (1)

Biotin Conjugated (1)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

PE Conjugated (1)

Unconjugated (7)

Publications

No (14)

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IHC-plus™ Chymotrypsin Antibody LS-B8028

(4.0) Rating

Antibody:

Chymotrypsin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

0.25 ml/$440

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Chymotrypsin Antibody LS-C293338

Antibody:

Chymotrypsin Rabbit anti-Bovine Polyclonal Antibody

Reactivity:

Bovine, Cow

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

20 µl/$266; 100 µl/$340; 200 µl/$395; 1 ml/$712

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Chymotrypsin Antibody (HRP) LS-C714857

Antibody:

Chymotrypsin Rabbit anti-Bovine Polyclonal (HRP) Antibody

Reactivity:

Bovine, Cow

Applications:

ICC, IP, WB

Format:

HRP Conjugated

Price:

100 µl/$378; 200 µl/$451; 1 ml/$897

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Chymotrypsin Antibody (Biotin) LS-C299378

Antibody:

Chymotrypsin Rabbit anti-Bovine Polyclonal (Biotin) Antibody

Reactivity:

Bovine, Cow

Applications:

ICC, IP, WB

Format:

Biotin Conjugated

Price:

100 µl/$353; 200 µl/$414; 1 ml/$783

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Chymotrypsin Antibody (FITC) LS-C696834

Antibody:

Chymotrypsin Rabbit anti-Bovine Polyclonal (FITC) Antibody

Reactivity:

Bovine, Cow

Applications:

ICC, IP, WB

Format:

FITC Conjugated

Price:

100 µl/$366; 200 µl/$432; 1 ml/$842

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Chymotrypsin Antibody (Cy3) LS-C705844

Antibody:

Chymotrypsin Rabbit anti-Bovine Polyclonal (Cy3) Antibody

Reactivity:

Bovine, Cow

Applications:

ICC, IP, WB

Format:

Cy3 Conjugated

Price:

100 µl/$469; 200 µl/$580; 1 ml/$1,233

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Chymotrypsin Antibody (APC, Cy7) LS-C742031

Antibody:

Chymotrypsin Rabbit anti-Bovine Polyclonal (APC, Cy7) Antibody

Reactivity:

Bovine, Cow

Applications:

ICC, IP, WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$598; 200 µl/$842; 1 ml/$1,849

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Chymotrypsin Antibody (PE) LS-C728929

Antibody:

Chymotrypsin Rabbit anti-Bovine Polyclonal (PE) Antibody

Reactivity:

Bovine, Cow

Applications:

ICC, IP, WB

Format:

PE Conjugated

Price:

100 µl/$366; 200 µl/$432; 1 ml/$842

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Chymotrypsin Antibody (APC) LS-C719946

Antibody:

Chymotrypsin Rabbit anti-Bovine Polyclonal (APC) Antibody

Reactivity:

Bovine, Cow

Applications:

ICC, IP, WB

Format:

APC Conjugated

Price:

100 µl/$404; 200 µl/$488; 1 ml/$1,001

• Unconjugated
• HRP
• Biotin
• FITC
• Cy3
• APC, Cy7
• PE
• More...
  • APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • Cy3
  • APC, Cy7
  • PE
  • APC

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Chymotrypsin Antibody LS-C121625

Antibody:

Chymotrypsin Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-Fr, IHC-P, WB

Format:

Unconjugated

Price:

200 µg/$732

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Chymotrypsin Antibody (clone CHYMO10-101.2) LS-C83045

Antibody:

Chymotrypsin Mouse anti-Human Monoclonal (CHYMO10-101.2) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$372; 500 µg/$533; 1 mg/$933

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Chymotrypsin Antibody (clone CHYMO10-104.5) LS-C83047

Antibody:

Chymotrypsin Mouse anti-Human Monoclonal (CHYMO10-104.5) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$372; 500 µg/$533; 1 mg/$933

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Chymotrypsin Antibody (clone CHYMO10-104.10) LS-C83048

Antibody:

Chymotrypsin Mouse anti-Human Monoclonal (CHYMO10-104.10) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$372; 500 µg/$533; 1 mg/$933

Select

Chymotrypsin Antibody LS-C83046

Antibody:

Chymotrypsin Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$372; 500 µg/$533; 1 mg/$933

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