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CHTF18 / RUVBL

CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)

Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH.

Gene Name: CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
Synonyms: CHTF18, C16orf41, C321D2.2, C321D2.4, C321D2.3 (novel protein), Ctf18, HCTF18, Homolog of yeast CHL12, C321D2.3, C321D2.4 (novel protein), CHL12, RUVBL
Target Sequences: Q8WVB6 Q8WVB6

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
CHTF18 / RUVBL (3)
No (3)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
CHTF18 / RUVBL Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CHTF18 / RUVBL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
107.2 kDa
20 µg/$150
CHTF18 / RUVBL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
107.2 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).