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Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1.
Gene Name: | chondroitin sulfate synthase 3 |
Synonyms: | CHSY3, Chondroitin synthase-2, Carbohydrate synthase 2, Chondroitin sulfate synthase 3, Chondroitin synthase 2, CHSY-2, CHSY2, CSS3 |
Target Sequences: | NP_787052.3 Q70JA7 |
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