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Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. No activity toward dermatan.
Gene Name: | carbohydrate (chondroitin 4) sulfotransferase 13 |
Synonyms: | CHST13, C4ST-3, C4ST3 |
Target Sequences: | Q8NET6 Q8NET6 |
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