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Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PARK2 transport into the mitochondria. In collaboration with PARK2, isoform 2 may enhance cell viability and protect cells from oxidative stress.
Gene Name: | chondroitin polymerizing factor |
Synonyms: | CHPF, CSS2, Chondroitin sulfate synthase 2, CHSY2 |
Target Sequences: | NM_024536 NP_078812.2 Q8IZ52 |
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