CHAF1A / CAF1

chromatin assembly factor 1, subunit A (p150)

Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity). Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.

☰ Filters

Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

CHAF1A / CAF1 (4)

Publications

No (4)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Select

Human CHAF1A / CAF1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65253

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

106.7 kDa

Price:

20 µg/$1,107

Select

Human CHAF1A / CAF1 Protein (Recombinant GST, N-terminus) (aa21-120) - LS-G61334

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human CHAF1A / CAF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75182

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

106.7 kDa

Price:

20 µg/$150

Select

CHAF1A / CAF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115933

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

106.7 kDa

Price:

100 µg/$494

Viewing 1-4 of 4 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.