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Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism.
Gene Name: | complement factor H-related 2 |
Synonyms: | CFHR2, CFHL2, Complement factor H-related 2, DDESK59, FHR2, HFL3, H factor (complement)-like 3, H factor-like 3, H factor-like protein 2, Factor H-related gene 2, FHR-2 |
Target Sequences: | NM_005666 NP_005657.1 P36980 |
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