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Complement factor D is a member of the trypsin family of peptidases. DF is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. Adipsin is a serine protease that is secreted by adipocytes into the bloodstream. Adipsin is equivalent to complement factor D and has a high level of expression in fat. This suggests a role for adipose tissue in immune system biology.
Gene Name: | complement factor D (adipsin) |
Family/Subfamily: | Protease , Serine S1 |
Synonyms: | CFD, ADIPSIN, C3 convertase activator, Complement factor D, Complement protein D, Complement factor D (adipsin), DF, ADN, Factor D, PFD, Properdin factor D |
Target Sequences: | NM_001928 NP_001919.2 P00746 |
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