CFB / Complement Factor B

complement factor B

CFB / Complement Factor B is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.

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Products

Proteins (19)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (2)

Recombinant (16)

Target

CFB / Complement Factor B (19)

Publications

No (19)

Tag

6His, C-terminus (2)

6His, N-terminus (1)

His (9)

His, N-Terminal (1)

His-GST (2)

His-MBP (1)

Myc-DDK (Flag) (3)

Species

Human (11)

Mouse (3)

Rat (4)

Source

293T Cells (1)

E. coli (13)

HEK 293 Cells (3)

Human Cells (1)

Mammalian Cells (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (3)

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Mouse CFB / Complement Factor B Protein (Recombinant 6His, N-terminus) (aa23-761) - LS-G20601

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

86.9 kD

Price:

100 µg/$500; 1 mg/$1,679; 20 µg/$364

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Human CFB / Complement Factor B Protein (Recombinant 6His, C-terminus) (Thr26-Leu764) - LS-G38857

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

84.07kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

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Human CFB / Complement Factor B Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65296

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

83 kDa

Price:

20 µg/$1,107

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Rat CFB / Complement Factor B Protein (Recombinant His-MBP) (aa34-159) - LS-G14639

Source:

E. coli

Tag:

His-MBP

Molecular Weight:

60.9 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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Human CFB / Complement Factor B Protein (Recombinant His) (aa270-388) - LS-G14624

Source:

E. coli

Tag:

His

Molecular Weight:

14.9 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Human CFB / Complement Factor B Protein (Recombinant His) - LS-G2697

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human CFB / Complement Factor B Protein (Recombinant His) - LS-G2759

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human CFB / Complement Factor B Protein (Recombinant His) (aa477-600) - LS-G14626

Source:

E. coli

Tag:

His

Molecular Weight:

15.4 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Mouse CFB / Complement Factor B Protein (Recombinant His) (aa32-157) - LS-G14630

Source:

E. coli

Tag:

His

Molecular Weight:

15.5 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$3,281

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Human CFB / Complement Factor B Protein (Recombinant His-GST) (aa35-160) - LS-G14632

Source:

E. coli

Tag:

His-GST

Molecular Weight:

41.3 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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CFB / Complement Factor B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99525

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.56 kDa

Price:

100 µg/$494

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Human CFB / Complement Factor B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75292

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.56 kDa

Price:

20 µg/$150

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Human CFB / Complement Factor B Protein (Recombinant His) (aa80-350) - LS-G141044

Source:

E. coli

Sequence Length:

270 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

29.81 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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Human CFB / Complement Factor B Protein (Recombinant 6His, C-terminus) (Thr26-Leu764) - LS-G139547

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

84.1 kDa

Price:

10 µg/$376; 50 µg/$526

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Human CFB / Complement Factor B Protein (Over-Expression Cell Culture Supernatant His, N-Terminal) (Thr26-Leu764) - LS-G136060

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~83 kDa

Price:

200 µl/$283

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Rat CFB / Complement Factor B Protein (Recombinant His) (aa269-382) - LS-G14629

Source:

E. coli

Tag:

His

Molecular Weight:

14.2 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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Rat CFB / Complement Factor B Protein (Recombinant His) (aa476-592) - LS-G14633

Source:

E. coli

Tag:

His

Molecular Weight:

15.1 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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Mouse CFB / Complement Factor B Protein (Recombinant His) (aa474-590) - LS-G14631

Source:

E. coli

Tag:

His

Molecular Weight:

15.0 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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Rat CFB / Complement Factor B Protein (Recombinant His-GST) (aa34-159) - LS-G14636

Source:

E. coli

Tag:

His-GST

Molecular Weight:

41.4 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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