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CFB / Complement Factor B

complement factor B

CFB / Complement Factor B is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.

Gene Name: complement factor B
Family/Subfamily: Protease , Serine S1
Synonyms: CFB, AHUS4, B-factor, properdin, C3/C5 convertase, CFAB, C3 proaccelerator, C3 proactivator, Complement factor B, Complement protein Factor B, Glycine-rich beta-glycoprotein, GBG, Factor B, FB, Glycine-rich beta glycoprotein, PBF2, BF, BFD, FBI12, H2-Bf, Properdin factor B
Target Sequences: NM_001710 NP_001701.2 P00751

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Products
ELISA Kits (26)
Competitive EIA (1)
Custom (3)
Sandwich (22)
CFB / Complement Factor B (26)
Human (8)
Mouse (6)
Rat (5)
Chicken (1)
Monkey (1)
Pig (1)
Porcine (1)
Rabbit (1)
Rhesus monkey (1)
96-Well Microplate (3)
96-Well Strip Plate (23)
No (26)
Cell Culture Supernatants (1)
Cell Supernatant (1)
Plasma (21)
Serum (21)
Tissue Homogenates (5)
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.39 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$854
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Human
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$730
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
3.13 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$863
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Microplate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CFB / Complement Factor B ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
25 - 500 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$805
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
31.25 - 2000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Rhesus monkey
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$901
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
CFB / Complement Factor B ELISA Kit
Select
Custom
96-Well Strip Plate
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$669
CFB / Complement Factor B ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
CFB / Complement Factor B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$798
CFB / Complement Factor B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CFB / Complement Factor B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$968
CFB / Complement Factor B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$1,018
CFB / Complement Factor B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CFB / Complement Factor B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 µg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$1,002
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
31.25 - 2000 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CFB / Complement Factor B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Supernatant, Plasma, Serum
1 Plate/$598
CFB / Complement Factor B ELISA Kit
Select
Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1 Plate/$610
CFB / Complement Factor B ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
CFB / Complement Factor B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
100 - 2500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
Viewing 1-25 of 26 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).