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Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs).
Gene Name: | centrosomal protein 72kDa |
Synonyms: | CEP72, Centrosomal protein 72kDa, Centrosomal protein of 72 kDa, KIAA1519 |
Target Sequences: | NM_018140 NP_060610.2 Q9P209 |
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