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GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.
Gene Name: | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 |
Synonyms: | ACAP1, Centaurin, beta 1, Centaurin-beta-1, Cnt-b1, KIAA0050, CENTB1 |
Target Sequences: | NM_014716 NP_055531.1 Q15027 |
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