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CENPU / MLF1IP
Centromere protein U
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression.
| Gene Name: | Centromere protein U |
| Synonyms: | CENPU, CENP-U, CENP50, CENPU50, Centromere protein U, ICEN24, KLIP1, Polo-box-interacting protein 1, MLF1-interacting protein, CENP-50, Centromere protein of 50 kDa, MLF1 interacting protein, MLF1IP, PBIP1 |
| Target Sequences: | NM_024629 NP_078905.2 Q71F23 |
Publications (2)
1
Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation. Kang YH, Park JE, Yu LR, Soung NK, Yun SM, Bang JK, Seong YS, Yu H, Garfield S, Veenstra TD, Lee KS. Molecular cell. 2006 24:409-22.
[PubMed:17081991]
2
Centromere protein U expression promotes non-small-cell lung cancer cell proliferation through FOXM1 and predicts poor survival. Wang X, Chen D, Gao J, Long H, Zha H, Zhang A, Shu C, Zhou L, Yang F, Zhu B, Wu W. Cancer management and research. 2018 December;10:6971-6984. [Full Text Article]
[PubMed:30588102]
[PMC:PMC6298391]
Related Antibodies: LS-C158151.
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Antibodies
(26)
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(2)
Type
Primary
(26)
Recombinant
(2)
Target
CENPU / MLF1IP
(28)
Reactivity
Human
(26)
Mouse
(1)
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(4)
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(4)
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(1)
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(3)
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(3)
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IHC
(10)
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(5)
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(23)
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(15)
ICC
(1)
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(2)
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(1)
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rabbit
(26)
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(4)
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(15)
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polyclonal pc
(26)
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(1)
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(1)
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(3)
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(3)
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(3)
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(1)
Unconjugated
(15)
Epitope
aa292-319
(7)
aa214-263
(4)
aa80-129
(4)
Publications
No
(27)
Yes
(1)
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GST
(1)
His
(1)
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Human
(2)
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(1)
Wheat Germ Extract
(1)
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Purified
(2)
CENPU / MLF1IP Rabbit anti-Human Polyclonal Antibody
Dog, Bovine, Human, Chimpanzee
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$515
CENPU / MLF1IP Rabbit anti-Human Polyclonal (aa292-319) Antibody
Human
WB
Unconjugated
400 µl/$393
CENPU / MLF1IP Rabbit anti-Human Polyclonal Antibody
Human
ICC, IHC, IHC-P
Unconjugated
50 µl/$375
CENPU / MLF1IP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
CENPU / MLF1IP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
100 µg/$360
CENPU / MLF1IP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$515
CENPU / MLF1IP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$515
CENPU / MLF1IP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
25 µl/$304
CENPU / MLF1IP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
25 µl/$304
CENPU / MLF1IP Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$282; 200 µl/$350
CENPU / MLF1IP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CENPU / MLF1IP Rabbit anti-Human Polyclonal (aa292-319) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
CENPU / MLF1IP Rabbit anti-Human Polyclonal (aa292-319) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
CENPU / MLF1IP Rabbit anti-Human Polyclonal (aa292-319) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
CENPU / MLF1IP Rabbit anti-Human Polyclonal (aa292-319) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
CENPU / MLF1IP Rabbit anti-Human Polyclonal (aa292-319) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
CENPU / MLF1IP Rabbit anti-Human Polyclonal (aa292-319) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
CENPU / MLF1IP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$357
CENPU / MLF1IP Rabbit anti-Human Polyclonal (aa214-263) Antibody
Human
WB
Unconjugated
100 µl/$424
CENPU / MLF1IP Rabbit anti-Human Polyclonal (aa214-263) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
CENPU / MLF1IP Rabbit anti-Human Polyclonal (aa214-263) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
CENPU / MLF1IP Rabbit anti-Human Polyclonal (aa80-129) Antibody
Human
WB
Unconjugated
100 µl/$424
CENPU / MLF1IP Rabbit anti-Human Polyclonal (aa80-129) (HRP) Antibody
Bovine, Human, Chimpanzee, Orangutan, Gibbon
WB
HRP Conjugated
100 µl/$469
CENPU / MLF1IP Rabbit anti-Human Polyclonal (aa80-129) (Biotin) Antibody
Bovine, Human, Chimpanzee, Orangutan, Gibbon
WB
Biotin Conjugated
100 µl/$469
CENPU / MLF1IP Rabbit anti-Human Polyclonal (aa80-129) (FITC) Antibody
Bovine, Human, Chimpanzee, Orangutan, Gibbon
WB
FITC Conjugated
100 µl/$469
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