Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro).
Gene Name: | centromere protein A |
Synonyms: | CENPA, Centromere autoantigen A, Centromere-specific histone, CenH3, Centromere protein A, Centromere protein A, 17kDa, CENP-A, Centromere protein A (17kD) |
Target Sequences: | NM_001809 NP_001800.1 P49450 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.