Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1.
Gene Name: | chymotrypsin-like elastase family, member 3A |
Family/Subfamily: | Protease , Serine S1 |
Synonyms: | CELA3A, ELA3, Elastase 1, Elastase-3A, Elastase 3A, pancreatic, Protease E, ELA3A, Elastase IIIA |
Target Sequences: | NM_005747 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.