CDKN2C / p18 INK4c

cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)

CDKN2C / p18 INK4c is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.

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Products

Proteins (12)

Type

Over-Expression Lysate (6)

Recombinant (6)

Target

CDKN2C / p18 INK4c (12)

Publications

No (12)

Tag

6His, N-terminus (2)

GST (1)

His (1)

Myc-DDK (Flag) (8)

Species

Human (9)

Source

293T Cells (3)

E. coli (3)

HEK 293 Cells (5)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

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Human CDKN2C / p18 INK4c Protein (Recombinant His) - LS-G1596

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human CDKN2C / p18 INK4c Protein (Recombinant 6His, N-terminus) (Met1-Gln168) - LS-G38775

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

20.3kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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Human CDKN2C / p18 INK4c Protein (Recombinant GST) (Full Length) - LS-G27879

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

44.22 kDa

Price:

10 µg/$479; 25 µg/$670

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CDKN2C / p18 INK4c Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107900

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.9 kDa

Price:

100 µg/$494

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Human CDKN2C / p18 INK4c Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75356

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.9 kDa

Price:

20 µg/$150

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Human CDKN2C / p18 INK4c Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75357

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.9 kDa

Price:

20 µg/$150

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Human CDKN2C / p18 INK4c Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75358

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.9 kDa

Price:

20 µg/$150

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CDKN2C / p18 INK4c Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118693

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.9 kDa

Price:

100 µg/$494

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CDKN2C / p18 INK4c Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G127298

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.9 kDa

Price:

100 µg/$494

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Human CDKN2C / p18 INK4c Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65325

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.9 kDa

Price:

20 µg/$1,107

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Human CDKN2C / p18 INK4c Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65328

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.9 kDa

Price:

20 µg/$1,107

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Human CDKN2C / p18 INK4c Protein (Recombinant 6His, N-terminus) (Met1-Gln168) - LS-G140120

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

20.3 kDa

Price:

10 µg/$317

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