CDK4

cyclin-dependent kinase 4

Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity. Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

☰ Filters

Products

Antibodies (100)

Type

Primary (100)

Target

CDK4 (100)

Reactivity

Human (83)

Mouse (49)

Rat (46)

Bovine (4)

Chimpanzee (6)

Dog (7)

Gibbon (6)

Monkey (8)

Pig (5)

Rabbit (7)

Sheep (5)

more less

Application

IHC (30)

IHC-Fr (1)

IHC-P (8)

WB (97)

Flo (8)

ELISA (31)

Func (2)

ICC (6)

IF (9)

IP (18)

Peptide-ELISA (2)

RNAi (1)

more less

Host

rabbit (77)

mouse (22)

goat (1)

Product Group

IHCPlus (1)

Isotype

IgG (46)

IgG1 (9)

IgG1,k (3)

IgG2a (4)

IgG2a,k (2)

Clonality

monoclonal mc (21)

polyclonal pc (79)

Clone

10B2179 (1)

1529CT850.162.73 (1)

4F11 (1)

AT6D10 (1)

DCS-156 (2)

DCS-35 (1)

IML-4 (3)

Format

APC (2)

APC Conjugated (5)

Azide-free (3)

Biotin Conjugated (9)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (9)

HRP Conjugated (9)

Magnetic beads Conjugated (1)

PE Conjugated (6)

Preservative Free (2)

Sepharose Conjugated (1)

Unconjugated (56)

more less

Epitope

aa6-295 (16)

C-Terminus (10)

aa219-246 (7)

aa273-305 (7)

N-Terminus (2)

1-50 aa, N-terminal (1)

aa1-20 (1)

aa1-303 (1)

aa1-50 (1)

aa201-303 (1)

aa211-304 (1)

aa253-303 (1)

aa272-303 (1)

aa279-300 (1)

aa283-303 (1)

aa291-303 (1)

pThr172 (1)

more less

Publications

No (100)

Select

CDK4 Antibody (clone 1529CT850.162.73) LS-C392591

Antibody:

CDK4 Mouse anti-Human Monoclonal (1529CT850.162.73) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

Select

CDK4 Antibody (aa273-305) LS-C99873

Antibody:

CDK4 Rabbit anti-Human Polyclonal (aa273-305) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

CDK4 Antibody (clone DCS-156) LS-C22048

Antibody:

CDK4 Mouse anti-Human Monoclonal (DCS-156) Antibody

Reactivity:

Human

Applications:

IHC, IHC-Fr, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$832

Select

CDK4 Antibody (phospho-Thr172) LS-C411605

Antibody:

CDK4 Rabbit anti-Human Polyclonal (pThr172) Antibody

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$287; 100 µl/$431

Select

CDK4 Antibody LS-C137013

Antibody:

CDK4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$332

Select

CDK4 Antibody (aa6-295) LS-C293584

Antibody:

CDK4 Rabbit anti-Human Polyclonal (aa6-295) Antibody

Reactivity:

Rat, Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

Select

CDK4 Antibody LS-C285719

Antibody:

CDK4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

CDK4 Antibody (aa219-246, Azide-free, HRP) LS-C254436

Antibody:

CDK4 Rabbit anti-Mouse Polyclonal (aa219-246) (Azide-free) (HRP) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

CDK4 Antibody (aa279-300) LS-C63193

Antibody:

CDK4 Rabbit anti-Human Polyclonal (aa279-300) Antibody

Reactivity:

Rabbit, Sheep, Rat, Human, Monkey

Applications:

IP, WB

Format:

Unconjugated

Price:

25 µl/$271

Select

CDK4 Antibody LS-C178280

Antibody:

CDK4 Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

CDK4 Antibody LS-C664527

Antibody:

CDK4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

CDK4 Antibody (clone 4F11) LS-C196880

Antibody:

CDK4 Mouse anti-Human Monoclonal (4F11) Antibody

Reactivity:

Human

Applications:

ELISA, IF, RNAi, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

CDK4 Antibody (Preservative Free) LS-C817885

Antibody:

CDK4 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC-P, IP, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

Select

CDK4 Antibody (aa273-305) LS-C320270

Antibody:

CDK4 Rabbit anti-Human Polyclonal (aa273-305) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

CDK4 Antibody (aa273-305, Biotin) LS-C254440

Antibody:

CDK4 Rabbit anti-Human Polyclonal (aa273-305) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

CDK4 Antibody (aa273-305, FITC) LS-C254441

Antibody:

CDK4 Rabbit anti-Human Polyclonal (aa273-305) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

CDK4 Antibody (aa273-305, Azide-free, HRP) LS-C254446

Antibody:

CDK4 Rabbit anti-Human Polyclonal (aa273-305) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

CDK4 Antibody (aa273-305, PE) LS-C254447

Antibody:

CDK4 Rabbit anti-Human Polyclonal (aa273-305) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

CDK4 Antibody (aa273-305, APC) LS-C254439

Antibody:

CDK4 Rabbit anti-Human Polyclonal (aa273-305) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• PE
• APC

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • PE
  • APC

Select

CDK4 Antibody LS-C330939

Antibody:

CDK4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

IHC-plus™ CDK4 Antibody (aa1-50) LS-B13047

(4.0) Rating

Antibody:

CDK4 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

CDK4 Antibody (Preservative Free) LS-C815551

Antibody:

CDK4 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P, IP, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

Select

CDK4 Antibody (aa1-20) LS-C22031

Antibody:

CDK4 Mouse anti-Human Monoclonal (aa1-20) Antibody

Reactivity:

Mouse, Rat, Pig, Human

Applications:

Func, IF, IP, WB

Format:

Unconjugated

Price:

500 µl/$887

Select

CDK4 Antibody (clone DCS-35) LS-C22049

Antibody:

CDK4 Mouse anti-Human Monoclonal (DCS-35) Antibody

Reactivity:

Mouse, Rat, Pig, Human

Applications:

Func, IF, IP, WB

Format:

Unconjugated

Price:

50 µg/$801

Select

CDK4 Antibody (aa201-303) LS-C407748

Antibody:

CDK4 Rabbit anti-Human Polyclonal (aa201-303) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Viewing 1-25 of 100 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Antibodies

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.