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CDH9 / Cadherin 9 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins.
Gene Name: | cadherin 9, type 2 (T1-cadherin) |
Family/Subfamily: | Cadherin , not assigned-Cadherin |
Synonyms: | CDH9, Cadherin-9, T1-cadherin, Cadherin 9 |
Target Sequences: | NM_016279 NP_057363.3 Q9ULB4 |
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