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CDH12 / Cadherin 12
cadherin 12, type 2 (N-cadherin 2)
CDH12 / Cadherin 12 is a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
| Gene Name: | cadherin 12, type 2 (N-cadherin 2) |
| Family/Subfamily: | Cadherin , not assigned-Cadherin |
| Synonyms: | CDH12, Brain cadherin, Cadherin-12, Br-cadherin, Brain-cadherin, Cadherin, neural type, 2, CDHB, N-cadherin 2, Neural type cadherin 2, Neuronal cadherin 2 |
| Target Sequences: | NM_004061 NP_004052.2 P55289 |
Publications (1)
1
An N-Cadherin 2 expressing epithelial cell subpopulation predicts response to surgery, chemotherapy and immunotherapy in bladder cancer10<sup> Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA, USA. simon.knott@cshs.org12<sup> Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA, USA. dan.theodorescu@cshs.org. Kenneth H Gouin rd # , Nathan Ing # , Jasmine T Plummer , Charles J Rosser , Bassem Ben Cheikh , Catherine Oh , Stephanie S Chen , Keith Syson Chan , Hideki Furuya , Warren G Tourtellotte , Simon R V Knott , Dan Theodorescu. Nature communications. 2021 Aug;12:4906. [Full Text Article]
[PubMed:34385456]
[PMC:PMC8361097]
Related Antibodies: LS-B11408.
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CDH12 / Cadherin 12
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CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal (aa62-90) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal (aa62-90) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal (aa62-90) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal (aa62-90) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal (aa62-90) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal (aa62-90) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal (aa62-90) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
CDH12 / Cadherin 12 Mouse anti-Human Monoclonal (1B4) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$423
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CDH12 / Cadherin 12 Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal (aa324-373) Antibody
Human
WB
Unconjugated
100 µl/$424
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal (aa324-373) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal (aa324-373) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal (aa324-373) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
CDH12 / Cadherin 12 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$412
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