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Infectious Disease
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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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Customer Service: (800) 227-6666 / (650) 697-3600
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CDH1 / E Cadherin
cadherin 1, type 1, E-cadherin (epithelial)
CDH1 / E Cadherin is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.
| Gene Name: | cadherin 1, type 1, E-cadherin (epithelial) |
| Family/Subfamily: | Cadherin , not assigned-Cadherin |
| Synonyms: | CDH1, CD324, CDHE, Cell-CAM 120/80, E Cadherin, E-Cadherin, ECAD, Epithelial cadherin, Arc-1, UVO, Cadherin-1, CAM 120/80, CD324 antigen, LCAM, Uvomorulin |
| Target Sequences: | NM_004360 NP_004351.1 P12830 |
Publications (4)
1
Expression, purification, and functional characterization of recombinant PTD-SARA. Huang C, Du R, Zhang P, Meng H, Jia H, Song Y, Li M, Zhang Y, Sun S. Acta biochimica et biophysica Sinica. 2011 43:110-7. (ICC)
[PubMed:21266541]
2
Comparison of Different In Vivo Incubation Sites to Produce Tissue-Engineered Small Intestine. Liu Y, Cromeens BP, Wang Y, Fisher K, Johnson J, Chakroff J, Besner GE. Tissue engineering. Part A. 2018 July;4:1138-1147. [Full Text Article]
[PubMed:29383981]
[PMC:PMC6033308]
Related Antibodies: LS-B12414.
3
Benefit of Physiologically Variable Over Pressure-Controlled Ventilation in a Model of Chronic Obstructive Pulmonary Disease: A Randomized Study. Andre Dos Santos Rocha, Roberta Südy, Davide Bizzotto, Miklos Kassai, Tania Carvalho, Raffaele L Dellacà, Ferenc Peták, Walid Habre. Frontiers in physiology. 2021 Jan;11:625777. [Full Text Article]
[PubMed:33519528]
[PMC:PMC7839245]
☰ Filters
Products
Proteins
(25)
Type
Over-Expression Lysate
(2)
Recombinant
(23)
Target
CDH1 / E Cadherin
(25)
Publications
No
(25)
Tag
6His, C-terminus
(2)
6His, N-terminus
(1)
Fc
(2)
GST
(1)
GST, N-terminus
(1)
His
(6)
His, N-Terminal
(2)
His, N-terminus
(1)
His,C-terminus
(2)
His-GST
(1)
His-S
(2)
Myc-DDK (Flag)
(3)
Species
Chicken
(1)
Human
(15)
Mouse
(3)
Pig
(1)
Rat
(4)
Source
293T Cells
(1)
E. coli
(10)
HEK 293 Cells
(4)
Human
(1)
Human Cells
(5)
Mammalian Cells
(2)
Wheat Germ Extract
(2)
Purification
Purified
(6)
Low Endotoxin Level
Low endotoxin level
(10)
E. coli
6His, N-terminus
64.42 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
E. coli
His, N-Terminal
20.7 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
293T Cells
Myc-DDK (Flag)
97.46 kDa
20 µg/$215
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
His, N-Terminal
~60 kDa (80-90 kDa reducing conditions)
10 µg/$289; 100 µg/$432; 50 µg/$360
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
78.4 kDa
100 µg/$721
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
103.8 kDa
100 µg/$721
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
78 kDa
100 µg/$721
HEK 293 Cells
Myc-DDK (Flag)
97.46 kDa
100 µg/$710
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
61.2kD
10 µg/$255; 50 µg/$321; 500 µg/$1,262; 1 mg/$1,627
HEK 293 Cells
Myc-DDK (Flag)
94.8 kDa
20 µg/$1,107
E. coli
210 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
23.21 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
E. coli
His, N-terminus
23.9kDa
20 µg/$270; 100 µg/$390
Human
None
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
61.2 kDa
10 µg/$255; 50 µg/$317
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
77 kDa
100 µg/$600
Wheat Germ Extract
GST
123.9 kDa
2 µg/$439
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
70 kDa
10 µg/$317; 50 µg/$524
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
87.1 kDa
100 µg/$600
E. coli
His
14.3 kDa
10 µg/$262; 50 µg/$339; 100 µg/$512; 200 µg/$642; 1 mg/$1,623; 500 µg/$1,214; 5 mg/$2,562; 2 mg/$1,796
E. coli
His-S
33.1 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
E. coli
His
11.0 kDa
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
E. coli
His-S
33.9 kDa
10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170
E. coli
His-GST
60.2 kDa
10 µg/$287; 50 µg/$480; 100 µg/$767; 200 µg/$957; 1 mg/$2,089; 500 µg/$1,617; 5 mg/$3,347; 2 mg/$2,278
E. coli
His
15.0 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
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product results
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