CDC20

cell division cycle 20

Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.

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Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

CDC20 (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human CDC20 Protein (Recombinant His, N-Terminal) (Gln218-Arg471) - LS-G132630

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

30kDa

Price:

10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Human CDC20 Protein (Recombinant GST) (Full Length) - LS-G27844

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

81.2 kDa

Price:

2 µg/$439

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Human CDC20 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81425

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.5 kDa

Price:

20 µg/$150

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Human CDC20 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G58061

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CDC20 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68091

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.5 kDa

Price:

20 µg/$1,107

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CDC20 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99388

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.5 kDa

Price:

100 µg/$494

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