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Plays a role as adhesion receptor functioning by homophilic interactions and by clustering. Recruits SH2 domain-containing proteins SH2D1A/SAP. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway. May serve as a marker for hematopoietic progenitor cells.
Gene Name: | CD84 molecule |
Family/Subfamily: | Immunoglobulin , not assigned-Immunoglobulin |
Synonyms: | CD84, CD84 antigen, Cell surface antigen MAX.3, CD84 molecule, HCD84, Hly9-beta, LY9B, Leukocyte antigen CD84, SLAMF5, MCD84, SLAM family member 5 |
Target Sequences: | NM_003874 NP_003865.1 Q9UIB8 |
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