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CD81

CD81 molecule

CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: CD81 molecule
Family/Subfamily: Tetraspan , not assigned-Tetraspan
Synonyms: CD81, CD81 antigen, CD81 molecule, CVID6, S5.7, TAPA1, TAPA-1, Tetraspanin-28, TSPAN28, Tspan-28
Target Sequences: NM_004356 NP_004347.1 P60033

Publications (7)

1
Potentials and capabilities of the Extracellular Vesicle (EV) Array. Jørgensen MM, Bæk R, Varming K. Journal of Extracellular Vesicles. 2015 4:26048. (IHC; Human) [PubMed:25862471] [PMC:PMC4393420] Related Antibodies: LS-B7347.
2
Characterization of a Cell-Culturing System for the Study of Contact-Independent Extracellular Vesicle Communication. Revenfeld ALS, Søndergaard EKL, Stensballe A, Bæk R, Jørgensen MM, Varming K. Journal of circulating biomarkers. 2016 February;5:3. (Human) [Full Text Article] [PubMed:28936251] [PMC:PMC5548315] Related Antibodies: LS-B7347.
3
Induction of a Regulatory Phenotype in CD3+ CD4+ HLA-DR+ T Cells after Allogeneic Mixed Lymphocyte Culture; Indications of Both Contact-Dependent and -Independent Activation. Revenfeld ALS, Bæk R, Jørgensen MM, Varming K, Stensballe A. International journal of molecular sciences. 2017 July;18:pii: E1603. (Human) [Full Text Article] [PubMed:28737722] [PMC:PMC5536089] Related Antibodies: LS-B7347.
4
An miRNA fingerprint using neural-enriched extracellular vesicles from blood plasma: towards a biomarker for amyotrophic lateral sclerosis/motor neuron disease. Sandra Anne Banack, Rachael Anne Dunlop, Paul Alan Cox. Open biology. 2020 Jun;10:200116. [Full Text Article] [PubMed:32574550] [PMC:PMC7333885]
5
Enrichment of Neurodegenerative Microglia Signature in Brain-Derived Extracellular Vesicles Isolated from Alzheimer's Disease Mouse Models. Satoshi Muraoka, Mark P Jedrychowski, Naotoshi Iwahara, Mohammad Abdullah, Kristen D Onos, Kelly J Keezer, Jianqiao Hu, Seiko Ikezu, Gareth R Howell, Steven P Gygi, Tsuneya Ikezu. Journal of proteome research. 2021 Mar;20:1733-1743. [Full Text Article] [PubMed:33534581] [PMC:PMC7944570] Related Antibodies: LS-C350457.
6
Exploring the molecular content of CHO exosomes during bioprocessing. Christoph Keysberg , Oliver Hertel , Louise Schelletter , Tobias Busche, Chiara Sochart, Jörn Kalinowski, Raimund Hoffrogge , Kerstin Otte, Thomas Noll. Applied microbiology and biotechnology. 2021 May;;105:3673-3689. [Full Text Article] [PubMed:33937930] [PMC:PMC8102462] Related Antibodies: LS-C108453.
7
Extracellular Vesicle (EV) Array: microarray capturing of exosomes and other extracellular vesicles for multiplexed phenotyping. Jorgensen M1, Baek R, Pedersen S, Sondergaard EK, Kristensen SR, Varming K. Journal of Extracellular Vesicles. 2013 Jun 18;2: [Full Text Article] [PubMed:24009888] [PMC:PMC3760630] Related Antibodies: LS-B7347, LS-C35761.
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CD81 ELISA Kit
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0.313 - 20 ng/ml
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CD81 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).