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CD71 / Transferrin Receptor

Transferrin Receptor

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

Gene Name: Transferrin Receptor
Family/Subfamily: Protease , Metallopeptidase M28B
Synonyms: TFRC, CD71, TFR1, TRFR, TFR, TR, CD71 antigen, p90, T9, Transferrin receptor, Transferrin receptor protein 1
Target Sequences: NM_003234 NP_003225.2 P02786

Publications (2)

1
LC3-dependent EV loading and secretion (LDELS) promotes TFRC (transferrin receptor) secretion via extracellular vesicles. Jackson O Gardner, Andrew M Leidal, Tan A Nguyen, Jayanta Debnath. Autophagy. 2023 May;19:1551-1561. [Full Text Article] [PubMed:36286616] [PMC:PMC10240981] Related Antibodies: LS-C171694.
2
HIV-1 Tat interacts with and regulates the localization and processing of amyloid precursor protein. Kim J, Yoon JH, Kim YS. PloS one. 2013 8:e77972. [Full Text Article] [PubMed:24312169] [PMC:PMC3843664] Related Antibodies: LS-B6156.

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Products
ELISA Kits (30)
Cell-Based (1)
Cell-Based Phosphorylation (1)
Competitive EIA (1)
Custom (4)
Sandwich (21)
Sandwich CLIA (2)
CD71 / Transferrin Receptor (30)
Human (10)
Mouse (9)
Rat (5)
Chicken (2)
Dog (1)
Guinea pig (1)
Monkey (1)
Pig (1)
Porcine (1)
Rabbit (1)
12 x 8-Well Microstrips (3)
96-Well Microplate (5)
96-Well Strip Plate (22)
No (30)
Adherent Cell Cultures (2)
Cell Culture Supernatants (1)
Cell Lysates (1)
Cell Supernatant (1)
Plasma (20)
Serum (20)
Tissue Homogenates (6)
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$715
CD71 / Transferrin Receptor ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$750
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
10 - 250 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Microplate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
CD71 / Transferrin Receptor ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
CD71 / Transferrin Receptor ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$798
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
CD71 / Transferrin Receptor ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
CD71 / Transferrin Receptor ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$783
CD71 / Transferrin Receptor ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$585
CD71 / Transferrin Receptor ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.819 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$559
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$1,002
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CD71 / Transferrin Receptor ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).