CD46

CD46 molecule, complement regulatory protein

Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

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Products

ELISA Kits (15)

Type

Custom (5)

Sandwich (9)

Sandwich CLIA (1)

Target

CD46 (15)

Reactivity

Human (6)

Mouse (1)

Rat (1)

Chicken (1)

Guinea pig (1)

Monkey (1)

Pig (1)

Porcine (1)

Rabbit (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (2)

96-Well Strip Plate (12)

Publications

No (15)

Sample Type

Plasma (5)

Saliva (1)

Serum (5)

Tissue Homogenates (1)

Urine (1)

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Human CD46 (Sandwich ELISA) ELISA Kit - LS-F24143

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

7.81 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Human CD46 (Sandwich ELISA) ELISA Kit - LS-F4514

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

12.5 - 800 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Saliva, Serum, Urine

Price:

1 Plate/$798

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Human CD46 (Sandwich ELISA) ELISA Kit - LS-F12016

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Bovine CD46 (Custom ELISA) ELISA Kit - LS-F16714

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Mouse CD46 (Custom ELISA) ELISA Kit - LS-F16716

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Rat CD46 (Custom ELISA) ELISA Kit - LS-F16715

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Pig CD46 (Custom ELISA) ELISA Kit - LS-F16717

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Human CD46 (Sandwich ELISA) ELISA Kit - LS-F37222

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

7.813 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human CD46 (CLIA) ELISA Kit - LS-F30077

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

6.25 - 400 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Guinea pig CD46 (Sandwich ELISA) ELISA Kit - LS-F45636

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.391 - 25 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Chicken CD46 (Sandwich ELISA) ELISA Kit - LS-F45638

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.391 - 25 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Monkey CD46 (Sandwich ELISA) ELISA Kit - LS-F45639

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

7.813 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Porcine CD46 (Sandwich ELISA) ELISA Kit - LS-F45640

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

7.813 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Rabbit CD46 (Sandwich ELISA) ELISA Kit - LS-F45641

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

0.313 - 20 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Human CD46 (Custom ELISA) ELISA Kit - LS-F50451

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$610

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