CD40

CD40 molecule, TNF receptor superfamily member 5

CD40 is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

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Products

ELISA Kits (19)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Custom (2)

Sandwich (15)

Target

CD40 (19)

Reactivity

Human (9)

Mouse (8)

Rat (1)

Dog (1)

Pig (1)

Format

96-Well Microplate (6)

96-Well Strip Plate (13)

Publications

No (19)

Sample Type

Adherent Cell Cultures (2)

Breast Milk (1)

Cell Culture Supernatants (6)

Cell Lysates (2)

Plasma (15)

Saliva (1)

Serum (15)

Tissue Homogenates (2)

Urine (2)

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Human CD40 (Sandwich ELISA) ELISA Kit - LS-F52

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

54.87 - 40000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

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Mouse CD40 (Sandwich ELISA) ELISA Kit - LS-F12822

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

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Human CD40 (Sandwich ELISA) ELISA Kit - LS-F49217

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Pig CD40 (Sandwich ELISA) ELISA Kit - LS-F20322

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse CD40 (Sandwich ELISA) ELISA Kit - LS-F228

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

2.058 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

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Human CD40 (Sandwich ELISA) ELISA Kit - LS-F2636

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Breast Milk, Cell Culture Supernatants, Plasma, Saliva, Serum, Urine

Price:

1 Plate/$699

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Mouse CD40 (Sandwich ELISA) ELISA Kit - LS-F2637

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$699

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Mouse/Human CD40 (Cell-Based ELISA) ELISA Kit - LS-F1869

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Mouse CD40 (Sandwich ELISA) ELISA Kit - LS-F8748

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$610

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Rat CD40 (Sandwich ELISA) ELISA Kit - LS-F9074

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$750

Select

Human CD40 (Sandwich ELISA) ELISA Kit - LS-F12823

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

Select

Human CD40 (Sandwich ELISA) ELISA Kit - LS-F37284

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

19.5 - 1250 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse CD40 (Sandwich ELISA) ELISA Kit - LS-F38284

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human CD40 (Sandwich ELISA) ELISA Kit - LS-F54982

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$671

Select

Bovine CD40 (Custom ELISA) ELISA Kit - LS-F20323

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Dog CD40 (Custom ELISA) ELISA Kit - LS-F20324

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Human CD40 (Sandwich ELISA) ELISA Kit - LS-F24444

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Urine

Price:

1 Plate/$624

Select

Mouse CD40 (Sandwich ELISA) ELISA Kit - LS-F24767

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$624

Select

Mouse/Human Phospho-CD40 (Thr254) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1411

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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