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CD39
ectonucleoside triphosphate diphosphohydrolase 1
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
| Gene Name: | ectonucleoside triphosphate diphosphohydrolase 1 |
| Synonyms: | ENTPD1, ATPDase, CD39, CD39 antigen, Ecto-apyrase, Ecto-ATPDase 1, Ecto-ATP diphosphohydrolase 1, Ecto-ATPase 1, NTPDase-1, NTPDase 1 |
| Target Sequences: | NM_001776 NP_001767.3 P49961 |
Publications (2)
1
The ENTPD1 promoter polymorphism -860 A > G (rs3814159) is associated with increased gene transcription, protein expression, CD39/NTPDase1 enzymatic activity, and thromboembolism risk. Maloney JP, Branchford BR, Brodsky GL, Cosmic MS, Calabrese DW, Aquilante CL, Maloney KW, Gonzalez JR, Zhang W, Moreau KL, Wiggins KL, Smith NL, Broeckel U, Di Paola J. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2017 July;31:2771-2784. [Full Text Article]
[PubMed:28302652]
[PMC:PMC6137499]
2
Immune related endonucleases and GTPases are not associated with tumor response in patients with advanced non-small cell lung cancer treated with checkpoint inhibitors. H O Ramdani, M Falk, L C Heukamp, S Schatz, M Tiemann, C Wesseler, L Diehl, E Schuuring, H J M Groen, F Griesinger. Pathology, research and practice. 2021 November;227:153651. [Full Text Article]
[PubMed:34673351]
Related Antibodies: LS-B13080.
☰ Filters
Products
Proteins
(13)
Type
Over-Expression Lysate
(4)
Recombinant
(9)
Target
CD39
(13)
Application
SDS-PAGE
(1)
Publications
No
(13)
Tag
6His, C-terminus
(1)
GST
(1)
His
(1)
His,C-terminus
(2)
His-GST
(1)
His-T7
(2)
Myc-DDK (Flag)
(5)
Species
Human
(5)
Mouse
(5)
Rat
(1)
Source
293T Cells
(2)
Baculovirus
(2)
E. coli
(3)
HEK 293 Cells
(3)
Mammalian Cells
(2)
Wheat Germ Extract
(1)
Purification
Purified
(2)
Low Endotoxin Level
Low endotoxin level
(4)
Biologically Active
Biologically active
(1)
E. coli
His-GST
59.7 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
Baculovirus
His,C-terminus
SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The secreted recombinant mouse ENTPD1 consists of 451 amino acids and has a calculated molecular mass of 51 kDa.
50 µg/$403; 500 µg/$1,745
HEK 293 Cells
Myc-DDK (Flag)
57.8 kDa
20 µg/$1,107
Wheat Germ Extract
GST
84.4 kDa
10 µg/$479; 25 µg/$670
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
51 kDa
50 µg/$710; 500 µg/$3,767
HEK 293 Cells
Myc-DDK (Flag)
53 kDa
100 µg/$494
293T Cells
Myc-DDK (Flag)
53 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
46 kDa
20 µg/$150
Mammalian Cells
6His, C-terminus
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$269; 50 µg/$372; 500 µg/$1,245; 1 mg/$1,627
HEK 293 Cells
Myc-DDK (Flag)
46 kDa
100 µg/$494
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
50.5 kDa
10 µg/$358; 50 µg/$458
E. coli
His-T7
32.2 kDa
50 µg/$412; 10 µg/$276; 200 µg/$822; 100 µg/$657; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
E. coli
His-T7
32.3 kDa
10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136
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product results
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