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Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
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CD32B
Fc fragment of IgG, low affinity IIb, receptor (CD32)
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
| Gene Name: | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
| Family/Subfamily: | Immunoglobulin , not assigned-Immunoglobulin |
| Synonyms: | FCGR2B, CD32, CD32 antigen, CD32B, CDw32, FCG2, FcRII-b, IgG Fc receptor II-b, Fc gamma RIIb, Fc-gamma RII-b, FCGR2, Fc-gamma-RIIb, IGFR2 |
| Target Sequences: | NM_004001 NP_003992.3 P31994 |
Publications (1)
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